| Format | Hardcover |
| ISBN | 9780387690568 |
| Publication Date | 23/10/2008 |
| Publisher | Springer |
| Manufacturer | Springer Verlag |
This book will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how the degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to targeting proteolysis for therapy.
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